Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHP) is the result of excessive, independent, and inappropriate production of parathyroid hormone (PTH). The aim of this work is to study the epidemiological, clinico-biological and therapeutic aspects of PHP.Materials and methods: This is a retrospective study of 34 patients hospitalized for the management of PHP in the Endocrinology Department of the Military Hospital of Tunis between March 1999 and July 2018....

IntroductionThe thresholds of late night salivary cortisol (LNSC) vary widely among studies due to differences in assay methodologies and in control groups. We aimed to verify the analytical performance of the LNSC by electrochimiluminescence assay (ECLIA) and to establish cut-off values of LNSC for the screening of Cushing’s syndrome (CS).MethodsPatients with suspected CS underwent screening tests inclu...

Introduction: Hypoparathyroidism (HPT) is an often under-diagnosed condition. It is imperative to diagnose it at an early stage and to initiate prompt treatment given the evolving potential of the disease.The aim of our study is to describe the epidemiological, clinical and paraclinical features of HPT.Patients and Methods: This is a retrospective study of 61 observations of HPT collected at the endocrinology department during a 12-year period.<p cla...

Introduction: Cochleovestibular disorders in patients with diabetes is not well known as compared to other complications. The aim of this study was to evaluate the epidemiological, clinical and paraclinical characteristics of cochleovestibular dysfunction in diabetes.Materials and Methods: This is a retrospective study of 100 diabetic patients. The patients had a clinical otological and vestibular examination as well as a tonal audiometry and a video nys...

Introduction: Gonadal tumors are rare in children. Because surgery is the primary treatment for ovarian tumors, ovarian salvage with fertility preservation and use of a minimally invasive surgical technique are important in children and adolescents. We report the case of an adolescent girl who was referred after bilateral annexectomy. Observation: This is a 14-year-old girl who just had her first menses. She has been followed the last year for an ovarian...

Introduction: Multiple endocrine neoplasia type 2 (MEN2) is a rare inherited disease characterized by the occurrence of medullary thyroid cancer (MTC) either isolated or associated with pheochromocytoma, primary hyperparathyroidism (PHP), or typical morphological features. Thus, we report two cases.Patient(1): A 27-year-old female patient with a marfanoid appearance, had a histologically confirmed conjunctival and mucosal ganglioneuromatosis, bilateral c...

Introduction: Empty sella syndrome (ESS) is a rare condition in which the sella turcica is partially or completely filled with cerebrospinal fluid. It can be primary or secondary. Ophthalmologic involvement is rare in primary empty sella Syndrome. It is described in only 1.6 to 16% of cases. Patients and methods: We report a retrospective study of 46 cases of ESS collected in the endocrinology department over the period from 1991 to 2020. The clinical an...

Introduction: Growth hormone (GH) treatment in congenital growth hormone deficiency (CGHD) is indicated to improve the prognosis of the statural prognosis. The aim of this study is to identify the predictive factors of a favorable response to GH therapy.Patients & Methods: This is a retrospective study, conducted over a period of 27 years, including 30 patients with CGHD treated with hormonal therapy.Results: The CGHD was diagn...

Introduction: Graves’ disease (GD) is the most common cause of hyperthyroidism in pediatric patients, up to 95% in some studies.Observation: We report the observation of a 6-year-old female who consulted for a behavioral disorder made of agitation and lack of concentration. She had a family history of autoimmune thyroid disease. On examination, an accelerated statural growth rate of +2DS was noted. She had a significant palpebral retraction without ...

IntroductionThe diabetic foot represents a public health problem with very important direct and indirect expenses. Multidisciplinary care and monitoring is essential. The aim of this Study was to describe the management of the diabetic foot in the endocrinology department.Materials and methodsIt was a retrospective study carried out in the Endocrinology and Diabetology department of the Hédi Chaker unive...